diff --git a/android/chaquopy-recipes/cryptography-50/patches/pyo3_no_interpreter.patch b/android/chaquopy-recipes/cryptography-50/patches/pyo3_no_interpreter.patch
index a2de01d8..d41bd462 100644
--- a/android/chaquopy-recipes/cryptography-50/patches/pyo3_no_interpreter.patch
+++ b/android/chaquopy-recipes/cryptography-50/patches/pyo3_no_interpreter.patch
@@ -1,8 +1,6 @@
 --- src-original/Cargo.toml
 +++ src/Cargo.toml
-@@ -29,7 +29,10 @@
- foreign-types = "0.3"
- foreign-types-shared = "0.1"
+@@ -30,7 +30,10 @@
  openssl = "0.10.80"
  openssl-sys = "0.9.116"
  pem = { version = "4", default-features = false }
@@ -12,3 +10,4 @@
 +pyo3 = { version = "0.29", features = ["abi3", "abi3t", "abi3-py310"] }
 +
  pyo3-build-config = { version = "0.29" }
+ self_cell = "1"
diff --git a/meshchatx.rsm b/meshchatx.rsm
index 1cf7f902..baee1e02 100644
Binary files a/meshchatx.rsm and b/meshchatx.rsm differ
diff --git a/tests/backend/test_android_cryptography_pyo3_patch.py b/tests/backend/test_android_cryptography_pyo3_patch.py
new file mode 100644
index 00000000..2c026261
--- /dev/null
+++ b/tests/backend/test_android_cryptography_pyo3_patch.py
@@ -0,0 +1,82 @@
+# SPDX-License-Identifier: 0BSD
+
+"""Chaquopy cryptography-50 pyo3 patch must apply to the 50.0.0 sdist Cargo.toml."""
+
+from __future__ import annotations
+
+import shutil
+import subprocess
+from pathlib import Path
+
+import pytest
+
+ROOT = Path(__file__).resolve().parents[2]
+PATCH = (
+    ROOT
+    / "android"
+    / "chaquopy-recipes"
+    / "cryptography-50"
+    / "patches"
+    / "pyo3_no_interpreter.patch"
+)
+META = ROOT / "android" / "chaquopy-recipes" / "cryptography-50" / "meta.yaml"
+
+# cryptography-50.0.0 sdist Cargo.toml (PyPI tarball).
+CARGO_TOML_50_0_0 = """\
+[workspace]
+resolver = "2"
+members = [
+    "src/rust/",
+    "src/rust/cryptography-cffi",
+    "src/rust/cryptography-crypto",
+    "src/rust/cryptography-keepalive",
+    "src/rust/cryptography-key-parsing",
+    "src/rust/cryptography-openssl",
+    "src/rust/cryptography-x509",
+    "src/rust/cryptography-x509-verification",
+]
+
+[workspace.package]
+version = "0.50.0"
+authors = ["The cryptography developers <cryptography-dev@python.org>"]
+edition = "2021"
+publish = false
+# This specifies the MSRV
+rust-version = "1.83.0"
+license = "Apache-2.0 OR BSD-3-Clause"
+
+[workspace.dependencies]
+asn1 = { version = "0.24.1", default-features = false }
+base64 = "0.23"
+cc = "1.2.63"
+cfg-if = "1"
+foreign-types = "0.3"
+foreign-types-shared = "0.1"
+openssl = "0.10.80"
+openssl-sys = "0.9.116"
+pem = { version = "4", default-features = false }
+pyo3 = { version = "0.29", features = ["abi3", "abi3t"] }
+pyo3-build-config = { version = "0.29" }
+self_cell = "1"
+
+[profile.release]
+overflow-checks = true
+"""
+
+
+@pytest.mark.skipif(shutil.which("patch") is None, reason="patch is required")
+def test_pyo3_no_interpreter_patch_applies_to_cryptography_50_0_0(tmp_path: Path) -> None:
+    assert META.read_text(encoding="utf-8").count('version: "50.0.0"') == 1
+    cargo = tmp_path / "Cargo.toml"
+    cargo.write_text(CARGO_TOML_50_0_0, encoding="utf-8")
+    result = subprocess.run(
+        ["patch", "-p1", "-i", str(PATCH)],
+        cwd=tmp_path,
+        check=False,
+        capture_output=True,
+        text=True,
+    )
+    assert result.returncode == 0, result.stderr or result.stdout
+    patched = cargo.read_text(encoding="utf-8")
+    assert patched.count('pyo3 = { version = "0.29", features = ["abi3", "abi3t", "abi3-py310"] }') == 1
+    assert patched.count('pyo3 = { version = "0.29", features = ["abi3", "abi3t"] }') == 0